A national workshop organized Indian Institute of Metals

New Horizons in Metallurgy, Materials, and Manufacturing

A national workshop organized by Indian Institute of Metals
December 14th - 16th 2020

Home Schedule Speakers

Fermentation derived cellulose (Bacterial Cellulose) for healthcare and environment

avatar Prof. Mudrika Khandelwal Department of Materials Science and Metallurgical Engineering
IIT Hyderabad
  • Bio

    Dr Mudrika Khandelwal is currently an associate professor in the Department of Materials Science and Metallurgical Engineering at IIT Hyderabad. Mudrika has been working to develop scientific solutions for societal problems (many of which are part of the SDGs, declared by the UN and priorities of the Indian Government) including antimicrobial materials for food packaging and controlling infectious diseases, materials for energy storage, and environmental remediation, using sustainable nanofibrous cellulosic materials. Her lab has developed food packaging materials which can keep tomatoes fresh for 30 days and herbal antimicrobial materials to prevent the most common fungal infection. Her group has incubated to take forward this technology. Earlier she has done her bachelors and masters of technology from IIT Bombay and Doctorate at University of Cambridge, UK. Her work has received the Gandhian Young Technological Innovation award in 2016. She is also the nominated and elected fellow to Indian National Young academy of Sciences and member to National Academy of Sciences, India. Recently, she has received the prestigious Young Engineer Award from Indian National Academy of Engineers.

  • Abstract

    Cellulose is the most common naturally occurring biopolymer and used extensively in several applications. Cellulose derived from bacterial fermentation process, called bacterial cellulose, offers several advantages in terms of purity, nanofibrous and highly porous morphology and high crystallinity. All these properties make bacterial cellulose a suitable matrix for carrying active ingredients of various length scales. We demonstrate bacterial cellulose based active nanofibrous composites for delivery of drug molecules, antimicrobial nanoparticles and antifungal herbal oils contained in microcapsules. The drug delivery from diclofenac loaded bacterial cellulose has been tuned for acute and chronic pain management by ex-situ modification. Silver nanoparticle loaded cellulose has been used to produce antimicrobial food packaging and improve shelf life. Further, bacterial cellulose is loaded with microcapsules containing antifungal herbal oil for double barrier release to produce patches for the mitigation of fungal infections.